Prague Airport - Ruzyne Airport

Aeroflot (Moscow-Sheremetyevo)
Aerosvit Airlines (Kiev)
Air Europa (Madrid)
Air France (Lyon, Paris-Charles de Gaulle)
Alitalia (Milan Malpensa, Rome-Fiumicino)
Austrian Airlines
- Austrian Arrows (Vienna)
bmi
- bmibaby (Birmingham (UK), Cardiff, Manchester (UK), Nottingham/East Midlands)
British Airways (London-Heathrow, London-Gatwick)
- British Airways operated by Sun Air of Scandinavia (Billund)
Bulgaria Air (Sofia)
Condor Airlines (Munich)
Czech Airlines (Abu Dhabi, Al Ain, Amsterdam, Athens, Baku, Barcelona, Beirut, Belgrade, Berlin-Tegel, Bratislava, Braunschweig, Brno, Brussels, Bucharest, Budapest, Cairo, Cologne/Bonn, Copenhagen, Cork, Dubai, Dublin, Düsseldorf, Edinburgh, Ekaterinburg, Frankfurt, Hamburg, Hanover, Helsinki, Istanbul, Kiev, Kosice, Krakow, Kuwait, Larnaca, Lisbon, Ljubljana, London-Gatwick, London-Heathrow, London-Stansted, Luxembourg, Madrid, Manchester(UK), Marseille, Milan-Malpensa, Minsk, Montréal, Moscow-Sheremetyevo, Munich, New York-JFK, Newark, Odessa, Oslo, Ostrava, Paris-Charles de Gaulle, Riga, Rome-Fiumicino, Sarajevo, Sharm El Sheikh, Skopje, Sliac, Sofia, Split, Stockholm-Arlanda, St. Petersburg, Stuttgart, Tallinn, Tbilisi, Tel Aviv, Thessaloniki, Toronto, Venice, Vienna, Vilnius, Yerevan, Zagreb, Zilina, Zürich)
easyJet (Basel, Dortmund, London-Gatwick, London-Stansted, Newcastle, Nottingham/East Midlands)
El Al (Tel Aviv)
Finnair (Helsinki)
Flybaboo (Geneva)
Flyglobespan (Edinburgh [Resumes November 2], Glasgow, Liverpool [Starts November])
Germanwings (Cologne/Bonn, Stuttgart)
Imair Airlines (Baku)
InterSky (Friedrichshafen)
Jat Airways (Belgrade)
Jet2.com (Belfast, Blackpool [begins 29 October], Leeds/Bradford)
KLM Royal Dutch Airlines (Amsterdam)
Korean Air (Seoul-Incheon)
LOT Polish (Warsaw)
Lufthansa (Düsseldorf, Frankfurt, Hamburg, Munich)
Malév Hungarian Airlines (Budapest)
Norwegian Air Shuttle (Bergen, Oslo, Trondheim)
Pulkovo Aviation Enterprise (St. Petersburg)
Scandinavian Airlines (Copenhagen, Stockholm-Arlanda)
- SAS Braathens (Oslo)
SkyEurope (Amsterdam, Barcelona, Dubrovnik, Milan-Bergamo, Naples, Nice, Paris-Ory, Rome-Fiumicino, Split, Torino (starts December 26, 2006))
Smart Wings (Amsterdam, Barcelona, Brussels, Burgas, Chania, Copenhagen, Gerona, Gran Canaria, Heraklion, Larnaca, Madrid, Málaga, Milan-Bergamo, Palma de Mallorca, Paris-Charles de Gaulle, Rome-Fiumicino, Thessaloniki, Venice, Zakinthos)
SN Brussels Airlines (Brussels)
Swiss International Air Lines (Zürich)
- Swiss European Air Lines (Zürich)
Thomsonfly (Doncaster-Sheffield, London-Gatwick, Manchester (UK))
Travel Service (Fuerteventura, Funchal, Lanzarote, London-Stansted, Madrid, Oslo, Sharm el-Sheik, Tenerife-South)
Tunisair (Tunis)
Windjet (Catania)